onsdag 23 maj 2012

Diabetes type II

Freely translated from Läkemedelsboken 2011-2012, published by Läkemedelsverket (the Swedish Medical Products Agency), page 584.


"In Diabetes type II there is a markedly decreased sensitivity to insulin in combination with gradually declining beta-cell function. The insulin resistance is mainly manifested by a lowered glucose uptake in muscles and increased gluconeogenesis in the liver. 


The metabolic syndrome encompasses obesity, hypertension, type-2 diabetes (lowered glucose tolerance), dyslipidemia and raised triglycerid levels and aterogenic changed LDL-particles.


Smoking contributes to a worsened peripheral insulin sensitivity.


2/3 of people with diabetes type 2 pass away in some form of cardio-vascular disease.


The metabolic disturbances tend to get worse over time. This means that patients that initially have coped with dietary restrictions, later need medication or insulin. Today over 50% of patients who suffered from type 2 diabetes for 10 years or more are treated with insulin.
"


The basis for all diabetes treatment is the diet, but here is a mind map of the medications you can take to treat diabetes type 2.


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