Freely translated from Läkemedelsboken 2011-2012, published by Läkemedelsverket (the Swedish Medical Products Agency), page 584.
"In Diabetes type II there is a markedly decreased sensitivity to insulin in combination with gradually declining beta-cell function. The insulin resistance is mainly manifested by a lowered glucose uptake in muscles and increased gluconeogenesis in the liver.
The metabolic syndrome encompasses obesity, hypertension, type-2 diabetes (lowered glucose tolerance), dyslipidemia and raised triglycerid levels and aterogenic changed LDL-particles.
Smoking contributes to a worsened peripheral insulin sensitivity.
2/3 of people with diabetes type 2 pass away in some form of cardio-vascular disease.
The metabolic disturbances tend to get worse over time. This means that patients that initially have coped with dietary restrictions, later need medication or insulin. Today over 50% of patients who suffered from type 2 diabetes for 10 years or more are treated with insulin.
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The basis for all diabetes treatment is the diet, but here is a mind map of the medications you can take to treat diabetes type 2.
Everything you need for the first two years of medschool. These links and mindmaps helped prepare me for the preclinical test at the Karolinska institute 2012. Couldn't have done it without them. Multimedia teaching assests are awesome.
onsdag 23 maj 2012
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